ALOX12 antibody (C-Term)

Catalog No. ABIN5518671

Product Details anti-ALOX12 Antibody

Target: ALOX12 (Arachidonate 12-Lipoxygenase (ALOX12))

Binding Specificity: AA 609-628, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALOX12 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Arachidonate 12-lipoxygenase, 12S-type(ALOX12) detection. Tested with WB in Human.

Sequence: HHKEKYFSGP KPKAVLNQFR

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Arachidonate 12-lipoxygenase, 12S-type(ALOX12) detection. Tested with WB in Human.
Gene Name: arachidonate 12-lipoxygenase
Protein Name: Arachidonate 12-lipoxygenase, 12S-type(12S-LOX/12S-lipoxygenase)

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human ALOX12(609-628aa HHKEKYFSGPKPKAVLNQFR), different from the related rat sequence by four amino acids, and from the related mouse sequence by five amino acids.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Sodium azide, Thimerosal (Merthiolate)

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for ALOX12

Target: ALOX12 (Arachidonate 12-Lipoxygenase (ALOX12))

Alternative Name: ALOX12 (ALOX12 Products)

Synonyms: 15-LOX-1 antibody, 15LOX-1 antibody, 12-LOX antibody, 12S-LOX antibody, LOG12 antibody, ALOX12 antibody, ALOX15 antibody, 9930022G08Rik antibody, Alox12p antibody, P-12LO antibody, 12-LO antibody, zgc:64120 antibody, wu:fb72a11 antibody, arachidonate 15-lipoxygenase antibody, arachidonate 12-lipoxygenase, 12S type antibody, arachidonate 12-lipoxygenase antibody, arachidonate 12-lipoxygenase, 12S-type antibody, ALOX15 antibody, ALOX12 antibody, Alox12 antibody, alox12 antibody, LOC100072916 antibody

Background: ALOX12, Arachidonate 12-lipoxygenase, is an enzyme that in humans is encoded by the ALOX12 gene. By fluorescence in situ hybridization, the ALOX12 gene is located in band 17p13.1. The gene consists of 14 exons with 13 introns and spans approximately 15 kb of DNAArachidonate 12-lipoxygenase introduces a molecular oxygen into the C-12 position of arachidonic acid to produce 12(S)-hydroperoxy-5,8,10,14-eicosatetraenoic acid. The major pathway of arachidonic acid metabolism in human platelets proceeds via a 12-lipoxygenase enzyme. Expression of the LOG12 gene was detected in human erythroleukemia cells, platelets, and human umbilical vein endothelial cells by reverse transcription-PCR analysis.

Synonyms: 12 LOX antibody|12(S) lipoxygenase antibody|12S LOX antibody|12S-lipoxygenase antibody|12S-LOX antibody|12S-type antibody|ALOX12 antibody|Alox12L antibody|Alox15 antibody|Arachidonate 12 lipoxygenase antibody|Arachidonate 12 lipoxygenase, 12S type antibody|Arachidonate 12 lipoxygenase, leukocyte type antibody|Arachidonate 12-lipoxygenase antibody|EC1.13.11.31 antibody|LOG12 antibody|LOX12_HUMAN antibody|Platelet type lipoxygenase 12 antibody|Platelet-type lipoxygenase 12 antibody

UniProt: P18054

Pathways: Positive Regulation of Endopeptidase Activity