ADAM2 antibody (N-Term)

Catalog No. ABIN5518722

This Rabbit Polyclonal antibody specifically detects ADAM2 in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ADAM2 antibody (N-Term) (ABIN5518722)

Target: ADAM2 (ADAM Metallopeptidase Domain 2 (ADAM2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAM2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ADAM2 Antibody

Binding Specificity: AA 231-274, N-Term

Purpose: Anti-ADAM2 Antibody Picoband®

Sequence: WIDENKIATT GEANELLHTF LRWKTSYLVL RPHDVAFLLV YREK

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-ADAM2 Antibody Picoband® (ABIN5518722). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human ADAM2, different from the related mouse and rat sequences by eleven amino acids.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. Burkin, H. R., Burkin, D. J., Davey, P. M., Griffin, D. K., Affara, N. A. Mapping, sequence, and expression analysis of the human fertilin beta gene (FTNB). Genomics 40: 190-192, 1997. 2. Gupta SK, Alves K, Palladino LO, Mark GE, Hollis GF (Aug 1996). "Molecular cloning of the human fertilin beta subunit". Biochem Biophys Res Commun 224 (2): 318-26.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for ADAM2

Target: ADAM2 (ADAM Metallopeptidase Domain 2 (ADAM2))

Alternative Name: ADAM2

Background:

Synonyms: Disintegrin and metalloproteinase domain-containing protein 2,ADAM 2,Cancer/testis antigen 15,CT15,Fertilin subunit beta,PH-30,PH30,PH30-beta,ADAM2,FTNB,

Tissue Specificity: Expressed specifically in spermatogenic cells in the seminiferous cells. Not detected in fetal tissues.

Background: ADAM2 (A Disintegrin and Metalloproteinase Domain 2), also known as FTNB or PH30, is an enzyme that in humans is encoded by the ADAM2 gene. This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions. This gene is mapped to 8p11.2.

Molecular Weight: 100 kDa

Gene ID: 2515

UniProt: Q99965