ANGPTL2 antibody (Middle Region)

Catalog No. ABIN5518733

This anti-ANGPTL2 antibody is a Rabbit Polyclonal antibody detecting ANGPTL2 in WB and IHC. Suitable for Human, Mouse and Rat.

Quick Overview for ANGPTL2 antibody (Middle Region) (ABIN5518733)

Target: ANGPTL2 (Angiopoietin-Like 2 (ANGPTL2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANGPTL2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ANGPTL2 Antibody

Binding Specificity: AA 275-312, Middle Region

Purpose: Anti-ANGPTL2 Antibody Picoband®

Sequence: WRDCLQALED GHDTSSIYLV KPENTNRLMQ VWCDQRHD

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-ANGPTL2 Antibody Picoband® (ABIN5518733). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human ANGPTL2, different from the related mouse sequence by one amino acid.

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Western blot, 0.1-0.5 μg/mL, Mouse, Rat, Human
1. "Entrez Gene: ANGPTL2 angiopoietin-like 2". 2. Kim I, Moon SO, Koh KN, Kim H, Uhm CS, Kwak HJ, Kim NG, Koh GY (Oct 1999). "Molecular cloning, expression, and characterization of angiopoietin-related protein. angiopoietin-related protein induces endothelial cell sprouting". J Biol Chem. 274 (37): 26523-8. 3. Sun H, Zheng JM, Chen S, et al. (2007). "Enhanced expression of ANGPTL2 in the microvascular lesions of diabetic glomerulopathy". Nephron Exp. Nephrol.105 (4): e117-23.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for ANGPTL2

Target: ANGPTL2 (Angiopoietin-Like 2 (ANGPTL2))

Alternative Name: ANGPTL2

Background:

Synonyms: Angiopoietin-related protein 2,Angiopoietin-like protein 2,ANGPTL2,ARP2,UNQ170/PRO196,

Tissue Specificity: Widely expressed in heart, small intestine, spleen and stomach. Also found in lower levels in colon, ovary, adrenal gland, skeletal muscle and in prostate.

Background: Angiopoietin-related protein 2, also known as angiopoietin-like protein 2, is a protein that in humans is encoded by the ANGPTL2 gene. Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. ANGPTL2 protein is a secreted glycoprotein with homology to the angiopoietins and may exert a function on endothelial cells through autocrine or paracrine action.

Molecular Weight: 57 kDa

Gene ID: 23452