Annexin VIII antibody (N-Term)

Catalog No. ABIN5518736

Product Details anti-Annexin VIII Antibody

Target: Annexin VIII (ANXA8) (Annexin A8 (ANXA8))

Binding Specificity: AA 20-61, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Annexin VIII antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purpose: Anti-Annexin VIII/ANXA8 Antibody Picoband®

Sequence: HFNPDPDAET LYKAMKGIGT NEQAIIDVLT KRSNTQRQQI AK

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Annexin VIII/ANXA8 Antibody Picoband® (ABIN5518736). Tested in Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Annexin VIII, different from the related mouse and rat sequences by one amino acid.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human1. Chambers, J. A., Gardner, E., Hauptmann, R., Ponder, B. A., Mulligan, L. M. TaqI polymorphisms at the annexin VIII locus (ANX8). Hum. Molec. Genet. 1: 550 only, 1992. 2. Chang, K.-S., Wang, G., Freireich, E. J., Daly, M., Naylor, S. L., Trujillo, J. M., Stass, S. A. Specific expression of the annexin VIIIgene in acute promyelocytic leukemia. Blood 79: 1802-1810, 1992. 3. Sarkar, A., Yang, P., Fan, Y.-H., Mu, Z. M., Hauptmann, R., Adolf, G. R., Stass, S. A., Chang, K.-S. Regulation of the expression ofannexin VIII in acute promyelocytic leukemia. Blood 84: 279-286, 1994.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

References for anti-Annexin VIII antibody (ABIN5518736)

Salenius, Haapanen, Harju, Jokela, Riekkinen: "Late carotid restenosis: aetiologic factors for recurrent carotid artery stenosis during long-term follow-up." in: European journal of vascular surgery, Vol. 3, Issue 3, pp. 271-7, (1989) (PubMed).

Target Details for Annexin VIII

Target: Annexin VIII (ANXA8) (Annexin A8 (ANXA8))

Alternative Name: ANXA8 (ANXA8 Products)

Background:

Synonyms: Annexin A8 ,Annexin VIII ,Annexin-8 ,Vascular anticoagulant-beta ,VAC-beta ,ANXA8 ,ANX8,

Tissue Specificity: Ubiquitously expressed.

Background: ANXA8 is also known as ANNEXIN VIII. This gene encodes a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. The encoded protein may function as an anticoagulant that inly inhibits the thromboplastin-specific complex. Overexpression of this gene has been associated with acute myelocytic leukemia. A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10.

Molecular Weight: 37 kDa

Gene ID: 653145

UniProt: P13928