IFNGR1 antibody (N-Term)

Catalog No. ABIN5518850

This anti-IFNGR1 antibody is a Rabbit Polyclonal antibody detecting IFNGR1 in WB and FACS. Suitable for Human.

Quick Overview for IFNGR1 antibody (N-Term) (ABIN5518850)

Target: IFNGR1 (Interferon gamma Receptor 1 (IFNGR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFNGR1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-IFNGR1 Antibody

Binding Specificity: AA 108-147, N-Term

Purpose: Anti-IFNGR1 Antibody Picoband®

Sequence: QKESAYAKSE EFAVCRDGKI GPPKLDIRKE EKQIMIDIFH

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-IFNGR1 Antibody Picoband® (ABIN5518850). Tested in Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human IFNGR1, different from the related mouse sequence by eighteen amino acids.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human1. "Entrez Gene: IFNGR1 interferon gamma receptor 1". 2. Aguet M, Dembi99 Z, Merlin G (Oct 1988). "Molecular cloning and expression of the human interferon-gamma receptor". Cell. 55 (2): 273-80. 3. Novick D, Orchansky P, Revel M, Rubinstein M (Jun 1987). "The human interferon-gamma receptor. Purification, characterization, and preparation of antibodies". The Journal of Biological Chemistry. 262(18): 8483-7.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for IFNGR1

Target: IFNGR1 (Interferon gamma Receptor 1 (IFNGR1))

Alternative Name: IFNGR1

Background:

Synonyms: Interferon gamma receptor 1,IFN-gamma receptor 1,IFN-gamma-R1,CDw119,CD119,IFNGR1,

Tissue Specificity: Liver and small intestine. Also found in ovary, testis and kidney.

Background: Interferon gamma receptor 1 (IFNGR1), also known as CD119 (Cluster of Differentiation 119), is a protein that in humans is encoded by the IFNGR1 gene. This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.

Molecular Weight: 95 kDa

Gene ID: 3459

UniProt: P15260

Pathways: Interferon-gamma Pathway