NDRG3 antibody (AA 181-239)

Catalog No. ABIN5518857

This Rabbit Polyclonal antibody specifically detects NDRG3 in WB and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for NDRG3 antibody (AA 181-239) (ABIN5518857)

Target: NDRG3 (NDRG Family Member 3 (NDRG3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDRG3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-NDRG3 Antibody

Binding Specificity: AA 181-239

Purpose: Anti-NDRG3 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-NDRG3 Antibody Picoband® (ABIN5518857). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human NDRG3 recombinant protein (Position: L181-R239). Human NDRG3 shares 93.1% and 94.9% amino acid (aa) sequence identity with mouse and rat NDRG3, respectively.

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Western blot, 0.1-0.5 μg/mL, Human
1. Kalaydjieva, L., Gresham, D., Gooding, R., Heather, L., Baas, F., de Jonge, R., Blechschmidt, K., Angelicheva, D., Chandler, D., Worsley, P., Rosenthal, A., King, R. H. M., Thomas, P. K. N-myc downstream-regulated gene 1 is mutated in hereditary motor and sensory neuropathy-Lom.Am. J. Hum. Genet. 67: 47-58, 2000. 2. Zhou, R.-H., Kokame, K., Tsukamoto, Y., Yutani, C., Kato, H., Miyata, T. Characterization of the human NDRG gene family: a newly identified member, NDRG4, is specifically expressed in brain and heart. Genomics 73: 86-97, 2001.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for NDRG3

Target: NDRG3 (NDRG Family Member 3 (NDRG3))

Alternative Name: NDRG3

Background:

Synonyms: Protein NDRG3,N-myc downstream-regulated gene 3 protein,NDRG3,

Tissue Specificity: Ubiquitous. Highly expressed in brain. .

Background: In studies of the NDRG gene family in the human, novel mouse sequences of Ndr2 and Ndr3 were used to search the human genome databases. This confirmed the existence of a human NDRG3 gene, homologous to mouse Ndr3. The 3 known human NDRG proteins show considerable homology, with 54 % amino acid sequence identity between NDRG1 and NDRG2, 67 % between NDRG1 and NDRG3, and 58 % between NDRG2 and NDRG3. The NDRG3 gene was represented by 86 ESTs and a genomic clone from chromosome 20q11.21-q11.23. This provisional chromosomal localization was confirmed by electronic PCR.

Molecular Weight: 41 kDa

Gene ID: 57446