Epigen antibody (AA 19-109)

Catalog No. ABIN5518911

This Rabbit Polyclonal antibody specifically detects Epigen in WB, ELISA and IHC. It exhibits reactivity toward Mouse and Rat.

Quick Overview for Epigen antibody (AA 19-109) (ABIN5518911)

Target: Epigen (EPGN) (Epithelial Mitogen (EPGN))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Epigen antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-Epigen Antibody

Binding Specificity: AA 19-109

Purpose: Anti-Epigen/Epgn Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Epigen/Epgn Antibody Picoband® (ABIN5518911). Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived mouse Epigen recombinant protein (Position: A19-K109). Mouse Epigen shares 82.8% amino acid (aa) sequence identity with human Epigen.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. "Entrez Gene: Epithelial mitogen". 2. Schneider MR, Yarden Y (2014). "Structure and function of epigen, the last EGFR ligand". Semin. Cell Dev. Biol. 28: 57-61.

Comment:

We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for Epigen

Target: Epigen (EPGN) (Epithelial Mitogen (EPGN))

Alternative Name: Epgn

Background:

Synonyms: Epigen,Epithelial mitogen,EPG,Epgn,

Background: Epigen also known as epithelial mitogen is a protein that in humans is encoded by the EPGN gene. The protein encoded by this gene is a member of the epidermal growth factor family. Members of this family are ligands for the epidermal growth factor receptor and play a role in cell survival, proliferation and migration. This protein has been reported to have high mitogenic activity but low affinity for its receptor. Expression of this transcript and protein have been reported in cancer specimens of the breast, bladder, and prostate.

Molecular Weight: 17 kDa

Gene ID: 71920

UniProt: Q924X1

Pathways: RTK Signaling, EGFR Signaling Pathway