IL17RA antibody (AA 53-284)

Catalog No. ABIN5518928

This anti-IL17RA antibody is a Rabbit Polyclonal antibody detecting IL17RA in WB and ELISA. Suitable for Human.

Quick Overview for IL17RA antibody (AA 53-284) (ABIN5518928)

Target: IL17RA (Interleukin 17 Receptor A (IL17RA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL17RA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IL17RA Antibody

Binding Specificity: AA 53-284

Purpose: Anti-L17A Receptor/IL17RA Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-L17A Receptor/IL17RA Antibody Picoband® (ABIN5518928). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human IL17RA recombinant protein (Position: K53-Q284). Human IL17RA shares 74.1% amino acid (aa) sequence identity with mouse IL17RA.

Isotype: IgG

Application Details

Application Notes: ELISA, 0.1-0.5 μg/mL, -, Western blot, 0.1-0.5 μg/mL, Human,
1. "Entrez Gene: IL17RA interleukin 17 receptor A". 2. Yao, Z., Spriggs, M. K., Derry, J. M. J., Strockbine, L., Park, L. S., VandenBos, T., Zappone, J., Painter, S. L., Armitage, R. J. Molecular characterization of the human interleukin (IL)-17 receptor. Cytokine 9: 794-800, 1997. 3. Yao, Z., Fanslow, W. C., Seldin, M. F., Rousseau, A.-M., Painter, S. L., Comeau, M. R., Cohen, J. I., Spriggs, M. K. Herpesvirus saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor. Immunity 3: 811-821, 1995.

Comment:

We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for IL17RA

Target: IL17RA (Interleukin 17 Receptor A (IL17RA))

Alternative Name: IL17RA

Background:

Synonyms: Interleukin-17 receptor A,IL-17 receptor A,IL-17RA,CDw217,CD217,IL17RA,IL17R,

Tissue Specificity: Widely expressed. .

Background: Interleukin 17 receptor A, also known as IL17RA and CDw217 (cluster of differentiation w217), is a human gene. The IL17R gene is mapped to 22q11.22-q11.23 by radiation hybrid analysis. Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis.

Molecular Weight: 120-150 kDa

Gene ID: 23765

UniProt: Q96F46

Pathways: SARS-CoV-2 Protein Interactome