IL17B antibody (AA 21-180)

Catalog No. ABIN5519012

This anti-IL17B antibody is a Rabbit Polyclonal antibody detecting IL17B in WB and ELISA. Suitable for Human, Rat and Mouse.

Quick Overview for IL17B antibody (AA 21-180) (ABIN5519012)

Target: IL17B (Interleukin 17B (IL17B))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL17B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IL17B Antibody

Binding Specificity: AA 21-180

Purpose: Anti-IL17B Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-IL17B Antibody Picoband® (ABIN5519012). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human IL17B recombinant protein (Position: Q21-F180).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Moseley TA, Haudenschild DR, Rose L, Reddi AH (April 2003). "Interleukin-17 family and IL-17 receptors". Cytokine Growth Factor Rev. 14 (2): 155-74. 2. Yamaguchi, Y., Fujio, K., Shoda, H., Okamoto, A., Tsuno, N. H., Takahashi, K., Yamamoto, K. IL-17B and IL-17C are associated with TNF-alpha production and contribute to the exacerbation of inflammatory arthritis. J. Immun. 179: 7128-7136, 2007.

Comment:

We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for IL17B

Target: IL17B (Interleukin 17B (IL17B))

Alternative Name: IL17B

Background:

Synonyms: Interleukin-17B, IL-17B, Cytokine Zcyto7, Interleukin-20, IL-20, Neuronal interleukin-17-related factor, IL17B, IL20, NIRF, ZCYTO7, UNQ516/PRO1031,

Tissue Specificity: Expressed in adult pancreas, small intestine, stomach, spinal cord and testis. Less pronounced expression in prostate, colon mucosal lining, and ovary.

Background: The protein encoded by this gene is a T cell-derived cytokine that shares sequence similarity with IL17. This cytokine was reported to stimulate the release of TNF alpha (TNF) and IL1 beta (IL1B) from a monocytic cell line. Immunohistochemical analysis of several nerve tissues indicated that this cytokine is primarily localized to neuronal cell bodies.

Molecular Weight: 17 kDa

Gene ID: 27190