CD81 antibody (Biotin)

Catalog No. ABIN5526908

This Mouse Monoclonal antibody specifically detects CD81 in FACS, WB, IP, ICC and IHC (p). It exhibits reactivity toward Human, Rabbit and Cat.

Quick Overview for CD81 antibody (Biotin) (ABIN5526908)

Target: CD81

Reactivity: Human, Rabbit, Cat

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD81 antibody is conjugated to Biotin

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: M38

Product Details anti-CD81 Antibody (Biotin)

Purpose: Anti-Hu CD81 Biotin

Cross-Reactivity (Details): Human, Feline (Cat), Rabbit

Characteristics: The antibody M38 reacts with an extracellular epitope of CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells.

Purification: Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.

Immunogen: MOLT-4 (human T-ALL cell line)

Isotype: IgG1

Application Details

Application Notes: Flow cytometry: recommended dilution: 1 μg/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for CD81

Target: CD81

Alternative Name: CD81

Background: CD81 Molecule,CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells, e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus.,S5.7, CVID6, TAPA1, TSPAN28

Gene ID: 975

UniProt: P60033

Pathways: Inositol Metabolic Process, Hepatitis C