CD81 antibody (Biotin)
Quick Overview for CD81 antibody (Biotin) (ABIN5526908)
Target
See all CD81 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- Anti-Hu CD81 Biotin
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Specificity
- The antibody M38 reacts with an extracellular epitope of CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells.
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Cross-Reactivity (Details)
- Human, Feline (Cat), Rabbit
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Purification
- Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.
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Immunogen
- MOLT-4 (human T-ALL cell line)
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Isotype
- IgG1
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Application Notes
- Flow cytometry: recommended dilution: 1 μg/mL.
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- Store at 2-8°C. Do not freeze.
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- CD81
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Alternative Name
- CD81
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Background
- CD81 Molecule,CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells, e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus.,S5.7, CVID6, TAPA1, TSPAN28
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Gene ID
- 975
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UniProt
- P60033
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Pathways
- Inositol Metabolic Process, Hepatitis C
Target
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