PRKACA/PRKACB antibody (C-Term)

Catalog No. ABIN5530443

The Rabbit Polyclonal anti-PRKACA/PRKACB antibody has been validated for WB and IHC (p). It is suitable to detect PRKACA/PRKACB in samples from Human and Mouse.

Quick Overview for PRKACA/PRKACB antibody (C-Term) (ABIN5530443)

Target: PRKACA/PRKACB (Prkaca,Prkacb)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRKACA/PRKACB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PRKACA/PRKACB Antibody

Binding Specificity: AA 292-319, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Prkaca/Prkacb antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 292-319 amino acids from the C-terminal region of mouse Prkaca/Prkacb.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for PRKACA/PRKACB

Target: PRKACA/PRKACB (Prkaca,Prkacb)

Alternative Name: Prkaca/Prkacb

Background: Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux.

Molecular Weight: 41 kDa

Gene ID: 18749

UniProt: P68181