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SMAD3 antibody (AA 127-156)

SMAD3 Reactivity: Human WB, IF, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5531926
  • Target See all SMAD3 Antibodies
    SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))
    Binding Specificity
    • 39
    • 33
    • 27
    • 27
    • 25
    • 12
    • 11
    • 8
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 127-156
    Reactivity
    • 232
    • 152
    • 134
    • 27
    • 9
    • 9
    • 8
    • 7
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 220
    • 25
    • 1
    Rabbit
    Clonality
    • 205
    • 41
    Polyclonal
    Conjugate
    • 124
    • 13
    • 12
    • 11
    • 8
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    This SMAD3 antibody is un-conjugated
    Application
    • 194
    • 100
    • 76
    • 73
    • 55
    • 53
    • 48
    • 48
    • 28
    • 13
    • 13
    • 8
    • 5
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This SMAD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-156 amino acids from the Central region of human SMAD3.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product SMAD3 Primary Antibody
  • Application Notes
    For WB starting dilution is: 1:1000

    For IF starting dilution is: 1:10~50

    For IHC-P starting dilution is: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    SMAD3 (SMAD, Mothers Against DPP Homolog 3 (SMAD3))
    Alternative Name
    SMAD3 (SMAD3 Products)
    Background
    The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.
    Molecular Weight
    48 kDa
    Gene ID
    4088
    UniProt
    P84022
    Pathways
    Cell Division Cycle, Chromatin Binding, Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity, Autophagy
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