RPS19 antibody (C-Term)

Catalog No. ABIN5532056

This Rabbit Polyclonal antibody specifically detects RPS19 in WB. It exhibits reactivity toward Human.

Quick Overview for RPS19 antibody (C-Term) (ABIN5532056)

Target: RPS19 (Ribosomal Protein S19 (RPS19))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPS19 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RPS19 Antibody

Binding Specificity: AA 105-133, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RPS19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 105-133 amino acids from the C-terminal region of human RPS19.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for RPS19

Target: RPS19 (Ribosomal Protein S19 (RPS19))

Alternative Name: RPS19

Background: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia (DBA), a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors, in a subset of patients. This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation, in addition to its ribosomal function. Higher expression levels of this gene in some primary colon carcinomas compared to matched normal colon tissues has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Molecular Weight: 16 kDa

Gene ID: 6223

UniProt: P39019

Pathways: Positive Regulation of Immune Effector Process, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly