SORD antibody (AA 211-239)

Catalog No. ABIN5532181

This anti-SORD antibody is a Rabbit Polyclonal antibody detecting SORD in WB. Suitable for Human.

Quick Overview for SORD antibody (AA 211-239) (ABIN5532181)

Target: SORD (Sorbitol Dehydrogenase (SORD))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SORD antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SORD Antibody

Binding Specificity: AA 211-239

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SORD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 211-239 amino acids from the Central region of human SORD.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SORD

Target: SORD (Sorbitol Dehydrogenase (SORD))

Alternative Name: SORD

Background: Sorbitol dehydrogenase (SORD, EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1, MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.

Molecular Weight: 38 kDa

Gene ID: 6652

UniProt: Q00796