Unc5c antibody (N-Term)

Catalog No. ABIN5532755

This Rabbit Polyclonal antibody specifically detects Unc5c in WB. It exhibits reactivity toward Human.

Quick Overview for Unc5c antibody (N-Term) (ABIN5532755)

Target: Unc5c (Unc-5 Homolog C (C. Elegans) (Unc5c))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Unc5c antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Unc5c Antibody

Binding Specificity: AA 88-117, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This UNC5C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-117 amino acids from the N-terminal region of human UNC5C.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.34 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for Unc5c

Target: Unc5c (Unc-5 Homolog C (C. Elegans) (Unc5c))

Alternative Name: UNC5C

Background: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. Also involved in corticospinal tract axon guidances independently of DCC. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (By similarity).

Molecular Weight: 103 kDa

Gene ID: 8633

UniProt: O95185