AMH antibody (AA 424-451)

Catalog No. ABIN5532823

This anti-AMH antibody is a Rabbit Polyclonal antibody detecting AMH in WB, FACS and IHC (p). Suitable for Human and Mouse.

Quick Overview for AMH antibody (AA 424-451) (ABIN5532823)

Target: AMH (Anti-Mullerian Hormone (AMH))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AMH antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-AMH Antibody

Binding Specificity: AA 424-451

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This AMH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 424-451 amino acids from the Central region of human AMH.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:2000

For IHC-P starting dilution is: 1:10~50

For FACS starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for AMH

Target: AMH (Anti-Mullerian Hormone (AMH))

Alternative Name: AMH

Background: Anti mullerian hormone (AMH) is a member of the TGF beta superfamily. It is secreted as a homodimeric 140kD disulphide linked precursor that is cleaved to release the mature 30kD homodimer. Originally classified as a foetal testicular hormone that inhibits Mullerian duct development, AMH is expressed post natally by immature Sertoli cells, and to a lesser degree by granulosa cells. AMH plays a role in testicular differentiation and in the regulation of ovarian follicle growth.

Molecular Weight: 59 kDa

Gene ID: 268

UniProt: P03971

Pathways: Negative Regulation of Hormone Secretion