AMH antibody (Middle Region)

Catalog No. ABIN950438

There is 1 publication for this product available. The Rabbit Polyclonal anti-AMH antibody is suitable to detect AMH in samples from Human and Mouse. It has been validated for WB and IHC (p).

Quick Overview for AMH antibody (Middle Region) (ABIN950438)

Target: AMH (Anti-Mullerian Hormone (AMH))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AMH antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-AMH Antibody

Binding Specificity: AA 430-460, Middle Region

Specificity: This antibody reacts to Anti-Muellerian Hormone.

Cross-Reactivity (Details): Species reactivity (tested):Human and Mouse.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 430~460 amino acids from the Central region of human AMH

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-AMH antibody (ABIN950438)

Segal, Kent, Wesche, Ng, Serra, Oulès, Kar, Emerton, Blackford, Darmanis, Miquel, Luong, Yamamoto, Bonham, Jassem, Heaton, Vigilante, King, Sancho, Teichmann, Quake, Nakauchi, Rashid: "Single cell analysis of human foetal liver captures the transcriptional profile of hepatobiliary hybrid progenitors." in: Nature communications, Vol. 10, Issue 1, pp. 3350, (2019) (PubMed).

Target Details for AMH

Target: AMH (Anti-Mullerian Hormone (AMH))

Alternative Name: Anti-Muellerian Hormone / AMH

Background: Anti mullerian hormone (AMH) is a member of the TGF beta superfamily. It is secreted as a homodimeric 140kD disulphide linked precursor that is cleaved to release the mature 30kD homodimer. Originally classified as a foetal testicular hormone that inhibits Mullerian duct development, AMH is expressed post natally by immature Sertoli cells, and to a lesser degree by granulosa cells. AMH plays a role in testicular differentiation and in the regulation of ovarian follicle growth.Synonyms: MIF, MIS, Muellerian-inhibiting factor, Muellerian-inhibiting substance

Gene ID: 268

NCBI Accession: NP_000470

Pathways: Negative Regulation of Hormone Secretion