Apelin antibody (AA 215-244)

Catalog No. ABIN5532824

This Rabbit Polyclonal antibody specifically detects Apelin in WB. It exhibits reactivity toward Human.

Quick Overview for Apelin antibody (AA 215-244) (ABIN5532824)

Target: Apelin (APLN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Apelin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Apelin Antibody

Binding Specificity: AA 215-244

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This APLNR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 215-244 amino acids from the Central region of human APLNR.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for Apelin

Target: Apelin (APLN)

Alternative Name: APLN

Background: This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified.

Molecular Weight: 43 kDa

Gene ID: 187

UniProt: P35414

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Activity, Feeding Behaviour