Coilin antibody (AA 157-186)

Catalog No. ABIN5532916

This anti-Coilin antibody is a Rabbit Polyclonal antibody detecting Coilin in WB. Suitable for Human.

Quick Overview for Coilin antibody (AA 157-186) (ABIN5532916)

Target: Coilin (COIL)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Coilin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Coilin Antibody

Binding Specificity: AA 157-186

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This COIL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 157-186 amino acids from the Central region of human COIL.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for Coilin

Target: Coilin (COIL)

Alternative Name: COIL

Background: The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14.

Molecular Weight: 63 kDa

Gene ID: 8161

UniProt: P38432

Pathways: Ribonucleoprotein Complex Subunit Organization