SMC3 antibody (AA 402-430)

Catalog No. ABIN5533355

This Rabbit Polyclonal antibody specifically detects SMC3 in WB. It exhibits reactivity toward Human.

Quick Overview for SMC3 antibody (AA 402-430) (ABIN5533355)

Target: SMC3 (Structural Maintenance of Chromosomes 3 (SMC3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMC3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SMC3 Antibody

Binding Specificity: AA 402-430

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SMC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 402-430 amino acids from the Central region of human SMC3.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SMC3

Target: SMC3 (Structural Maintenance of Chromosomes 3 (SMC3))

Alternative Name: SMC3

Background: This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein.

Molecular Weight: 142 kDa

Gene ID: 9126

UniProt: Q9UQE7

Pathways: Stem Cell Maintenance