TIAM2 antibody (N-Term)

Catalog No. ABIN5534733

The Rabbit Polyclonal anti-TIAM2 antibody has been validated for WB. It is suitable to detect TIAM2 in samples from Mouse.

Quick Overview for TIAM2 antibody (N-Term) (ABIN5534733)

Target: TIAM2 (T-Cell Lymphoma Invasion and Metastasis 2 (TIAM2))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIAM2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TIAM2 Antibody

Binding Specificity: AA 357-385, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TIAM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 357-385 amino acids from the N-terminal region of human TIAM2.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for TIAM2

Target: TIAM2 (T-Cell Lymphoma Invasion and Metastasis 2 (TIAM2))

Alternative Name: TIAM2

Background: This gene encodes a guanine nucleotide exchange factor. A highly similar mouse protein specifically activates ras-related C3 botulinum substrate 1, converting this Rho-like guanosine triphosphatase (GTPase) from a guanosine diphosphate-bound inactive state to a guanosine triphosphate-bound active state. The encoded protein may play a role in neural cell development. Alternatively spliced transcript variants encoding different isoforms have been described.

Molecular Weight: 190 kDa

Gene ID: 26230

UniProt: Q8IVF5

Pathways: Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha