CDH10 antibody (C-Term)

Catalog No. ABIN5535226

Product Details anti-CDH10 Antibody

Target: CDH10 (Cadherin 10, Type 2 (T2-Cadherin) (CDH10))

Binding Specificity: AA 495-523, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDH10 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CDH10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 495-523 amino acids from the C-terminal region of human CDH10.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

For FACS starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.47 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for CDH10

Target: CDH10 (Cadherin 10, Type 2 (T2-Cadherin) (CDH10))

Alternative Name: CDH10 (CDH10 Products)

Synonyms: A830016G23Rik antibody, C030003B10Rik antibody, C030011H18Rik antibody, cadherin 10 antibody, Cdh10 antibody, CDH10 antibody

Background: CDH10 is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is predominantly expressed in brain and is putatively involved in synaptic adhesions, axon outgrowth and guidance.

Molecular Weight: 88 kDa

Gene ID: 1008

UniProt: Q9Y6N8

Pathways: Cell-Cell Junction Organization