ACTR1A antibody (AA 98-126)

Catalog No. ABIN5535443

This Rabbit Polyclonal antibody specifically detects ACTR1A in WB. It exhibits reactivity toward Mouse.

Quick Overview for ACTR1A antibody (AA 98-126) (ABIN5535443)

Target: ACTR1A (Alpha Centractin (ACTR1A))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACTR1A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ACTR1A Antibody

Binding Specificity: AA 98-126

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ACTR1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-126 amino acids from the Central region of human ACTR1A.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for ACTR1A

Target: ACTR1A (Alpha Centractin (ACTR1A))

Alternative Name: ACTR1A

Background: This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60 % identical at the amino acid level to conventional actin.

Molecular Weight: 43 kDa

Gene ID: 10121

UniProt: P61163

Pathways: M Phase