XPO1 antibody (C-Term)
Quick Overview for XPO1 antibody (C-Term) (ABIN5536022)
Target
See all XPO1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 817-846, C-Term
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Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
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Immunogen
- This XPO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 817-846 amino acids from the C-terminal region of human XPO1.
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Isotype
- Ig Fraction
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Application Notes
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For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 2 mg/mL
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Buffer
- Supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- XPO1 (Exportin 1 (XPO1))
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Alternative Name
- XPO1
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Background
- XPO1 mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.
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Molecular Weight
- 123 kDa
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Gene ID
- 7514
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UniProt
- O14980
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Pathways
- M Phase
Target
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