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XPO1 antibody (C-Term)

This Rabbit Polyclonal antibody specifically detects XPO1 in WB, FACS and IHC (p). It exhibits reactivity toward Human and Mouse.
Catalog No. ABIN5536022

Quick Overview for XPO1 antibody (C-Term) (ABIN5536022)

Target

See all XPO1 Antibodies
XPO1 (Exportin 1 (XPO1))

Reactivity

  • 80
  • 37
  • 37
  • 8
  • 7
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Mouse

Host

  • 73
  • 6
  • 1
Rabbit

Clonality

  • 62
  • 18
Polyclonal

Conjugate

  • 45
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This XPO1 antibody is un-conjugated

Application

  • 51
  • 24
  • 18
  • 14
  • 14
  • 13
  • 12
  • 9
  • 7
  • 7
  • 4
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Binding Specificity

    • 15
    • 10
    • 7
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 817-846, C-Term

    Purification

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

    Immunogen

    This XPO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 817-846 amino acids from the C-terminal region of human XPO1.

    Isotype

    Ig Fraction
  • Application Notes

    For WB starting dilution is: 1:1000

    For IHC-P starting dilution is: 1:50~100

    For FACS starting dilution is: 1:10~50

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    2 mg/mL

    Buffer

    Supplied in PBS with 0.09 % (W/V) sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target

    XPO1 (Exportin 1 (XPO1))

    Alternative Name

    XPO1

    Background

    XPO1 mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.

    Molecular Weight

    123 kDa

    Gene ID

    7514

    UniProt

    O14980

    Pathways

    M Phase
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