This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This TRAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 542-570 amino acids from the C-terminal region of human TRAP1.
TRAP1
Reactivity: Human
WB, IF
Host: Mouse
Polyclonal
unconjugated
Application Notes
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Restrictions
For Research Use only
Format
Liquid
Concentration
0.5 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
TRAP1
(TNF Receptor-Associated Protein 1 (TRAP1))
Alternative Name
TRAP1
Background
HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. TRAP1 is a mitochondrial HSP90 protein. Other HSP90 proteins are found in cytosol (see HSP90AA1, MIM 140571) and endoplasmic reticulum (HSP90B1, MIM 191175) (Chen et al., 2005 [PubMed 16269234]).