FRS2 antibody (Internal Region)

Catalog No. ABIN5539651

This anti-FRS2 antibody is a Goat Polyclonal antibody detecting FRS2 in WB and ELISA. Suitable for Mouse.

Quick Overview for FRS2 antibody (Internal Region) (ABIN5539651)

Target: FRS2 (Fibroblast Growth Factor Receptor Substrate 2 (FRS2))

Reactivity: Mouse

Host: Goat

Clonality: Polyclonal

Conjugate: This FRS2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Verified

Product Details anti-FRS2 Antibody

Binding Specificity: Internal Region

Purpose: FRS2

Sequence: SRDEDDNLGP KTPS

Specificity: Reported variants represent identical protein: NP_001265284.1, NP_001265286.1, NP_001265283.1, NP_001265285.1, NP_001265282.1, NP_006645.3, NP_001036020.1, NP_001265280.1

Cross-Reactivity: Cow, Dog, Human, Mouse, Pig

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Isotype: IgG

Application Details

Application Notes:

Western Blot: Approx 60 kDa band observed in lysates of undifferentiated cell line 3T3-L1 (calculated MW of 57.0 kDa according to NP_006645.3). Recommended concentration: 0.1-0.3 μg/mL. Primary incubation was 1 hour. Preliminary testing was unsuccessful on

Peptide ELISA: antibody detection limit dilution 1:128000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for FRS2

Target: FRS2 (Fibroblast Growth Factor Receptor Substrate 2 (FRS2))

Alternative Name: FRS2

Background: FRS2, fibroblast growth factor receptor substrate 2, FRS2A, FRS2alpha, SNT, SNT-1, SNT1, FGFR signalling adaptor, FGFR substrate 2, FGFR-signaling adaptor SNT, suc1-associated neurotrophic factor target 1

Gene ID: 10818, 327826

NCBI Accession: NP_006645

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Signaling Events mediated by VEGFR1 and VEGFR2