Neuroligin 4 antibody (AA 51-65)

Catalog No. ABIN5539745

This Goat Polyclonal antibody specifically detects Neuroligin 4 in WB and ELISA. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for Neuroligin 4 antibody (AA 51-65) (ABIN5539745)

Target: Neuroligin 4 (NLGN4)

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This Neuroligin 4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Verified

Product Details anti-Neuroligin 4 Antibody

Binding Specificity: AA 51-65

Purpose: NLGN4X (aa51-65)

Sequence: NYGKIRGLRT PLPNE

Specificity: Reported variants represent identical protein: NP_851849.1, NP_065793.1

Cross-Reactivity: Cow, Dog, Human, Pig

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Isotype: IgG

Application Details

Application Notes:

Western Blot: Approx 90 kDa band observed in Human Brain (Amygdala) lysates (calculated MW of 91.9 kDa according to NP_065793.1). Recommended concentration: 1-3 μg/mL.

Peptide ELISA: antibody detection limit dilution 1:128000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

References for anti-Neuroligin 4 antibody (ABIN5539745)

Marro, Chanda, Yang, Janas, Valperga, Trotter, Zhou, Merrill, Yousif, Shelby, Vogel, Kalani, Südhof, Wernig: "Neuroligin-4 Regulates Excitatory Synaptic Transmission in Human Neurons." in: Neuron, Vol. 103, Issue 4, pp. 617-626.e6, (2019) (PubMed).

Target Details for Neuroligin 4

Target: Neuroligin 4 (NLGN4)

Alternative Name: NLGN4X

Background: NLGN4X, neuroligin 4, X-linked, ASPGX2, AUTSX2, HLNX, HNL4X, HNLX, KIAA1260, MGC22376, NLGN, NLGN4, OTTHUMP00000022863, OTTHUMP00000022864, OTTHUMP00000022865, neuroligin X, neuroligin-4, X-linked

Gene ID: 57502

NCBI Accession: NP_065793

Pathways: Cell-Cell Junction Organization, Synaptic Membrane