Ghrelin antibody (N-Term)

Catalog No. ABIN5539939

This anti-Ghrelin antibody is a Mouse Monoclonal antibody detecting Ghrelin in IHC (p) and IHC (fro). Suitable for Human and Pig. This Primary Antibody has been cited in 1 publication.

Quick Overview for Ghrelin antibody (N-Term) (ABIN5539939)

Target: Ghrelin (GHRL)

Reactivity: Human, Pig

Host: Mouse

Clonality: Monoclonal

Conjugate: This Ghrelin antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 1ML-1D7

Product Details anti-Ghrelin Antibody

Binding Specificity: N-Term

Specificity: This antibody recognizes Ghrelin. The epitope is located on the N-terminal side of the peptide.

Purification: Affinity Chromatography

Immunogen: Synthetic peptide corresponding to the N-terminal 18 residues of Human Ghrelin.

Isotype: IgG1

Application Details

Application Notes: Immunohistochemistry on Frozen Sections: Suggested Positive Control: Human /porcine stomach.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, pH 7.2 Preservatives: 0.01 % Kathon Stabilizers: 5 mg/mL BSA

Storage: 4 °C,-20 °C

Storage Comment: Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

References for anti-Ghrelin antibody (ABIN5539939)

Mazzoni, Karunaratne, Sirri, Petracci, De Giorgio, Sternini, Clavenzani: "Enteroendocrine profile of α-transducin and α-gustducin immunoreactive cells in the chicken (Gallus domesticus) gastrointestinal tract." in: Poultry science, Vol. 97, Issue 11, pp. 4063-4072, (2018) (PubMed).

Target Details for Ghrelin

Target: Ghrelin (GHRL)

Alternative Name: ghrelin,ghrl

Background: Ghrelin is the only known peripheral orexigenic hormone. It is a 28 amino acid peptide, octanoylated at the serine 3 residue, which is principally secreted from endocrine cells in the stomach. Besides its orexigenic role, ghrelin regulates central and peripheral lipid metabolism through specific control of hypothalamic AMP - activated protein kinase (AMPK), thus regulating both cellular and whole - body energy homeostasis.

UniProt: Q9UBU3

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Peptide Hormone Metabolism, Negative Regulation of Hormone Secretion, Synaptic Membrane, Feeding Behaviour