Aggrecan antibody
Quick Overview for Aggrecan antibody (ABIN5539987)
Target
See all Aggrecan (ACAN) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- Monoclonal Ab 4G4/A10 is specific for a core protein epitope of Human articular cartilage. Therefore, in addition to applications in immunochemistry and immunohistochemistry, the 4G4/A10 monoclonal antibody can be used for the detection of aggrecan core protein fragments released during Human inflammatory or degenerative joint diseases into synovial fluid and serum. Species: Human.
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Purification
- Protein G Chromatography
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Immunogen
- Purified Human Aggrecan
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Isotype
- IgG1
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Application Notes
- ELISA: Less than 1 μg/mL (Ref.1) Western Blot: 1 μg/mL Immunohistochemistry:
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Restrictions
- For Research Use only
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Buffer
- 50 mM TRIS pH 7.4 without preservatives
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Preservative
- Without preservative
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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Expiry Date
- 12 months
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- Aggrecan (ACAN)
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Alternative Name
- aggrecan
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Background
- Aggrecan is the major proteoglycan of human articular cartilage. The core protein is substituted by a number of keratan sulfate and chondroitin sulfate glycosaminoglycan chains.
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UniProt
- P16112
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Pathways
- Glycosaminoglycan Metabolic Process, Dicarboxylic Acid Transport
Target
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