Aggrecan antibody

Catalog No. ABIN5539987

The Mouse Monoclonal anti-Aggrecan antibody (Clone 4G4-A10) (ABIN5539987) specifically detects Aggrecan in WB, IHC (p) and EIA. The antibody is reactive with Human samples.

Quick Overview for Aggrecan antibody (ABIN5539987)

Target: Aggrecan (ACAN)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Aggrecan antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Clone: 4G4-A10

Product Details anti-Aggrecan Antibody

Specificity: Monoclonal Ab 4G4/A10 is specific for a core protein epitope of Human articular cartilage. Therefore, in addition to applications in immunochemistry and immunohistochemistry, the 4G4/A10 monoclonal antibody can be used for the detection of aggrecan core protein fragments released during Human inflammatory or degenerative joint diseases into synovial fluid and serum. Species: Human.

Purification: Protein G Chromatography

Immunogen: Purified Human Aggrecan

Isotype: IgG1

Application Details

Application Notes: ELISA: Less than 1 μg/mL (Ref.1) Western Blot: 1 μg/mL Immunohistochemistry:

Restrictions: For Research Use only

Handling

Buffer: 50 mM TRIS pH 7.4 without preservatives

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for Aggrecan

Target: Aggrecan (ACAN)

Alternative Name: aggrecan

Background: Aggrecan is the major proteoglycan of human articular cartilage. The core protein is substituted by a number of keratan sulfate and chondroitin sulfate glycosaminoglycan chains.

UniProt: P16112

Pathways: Glycosaminoglycan Metabolic Process, Dicarboxylic Acid Transport