CBR1 antibody (AA 1-277)

Catalog No. ABIN5540084

This Mouse Monoclonal antibody specifically detects CBR1 in WB, ICC, IF, FACS and EIA. It exhibits reactivity toward Human.

Quick Overview for CBR1 antibody (AA 1-277) (ABIN5540084)

Target: CBR1 (Carbonyl Reductase 1 (CBR1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CBR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Clone: AT2D6

Product Details anti-CBR1 Antibody

Binding Specificity: AA 1-277

Purification: Protein-A affinity chromatography

Immunogen: Recombinant human CBR1 (1-277aa) purified from E. coli.

Isotype: IgG2a

Application Details

Application Notes: The antibody has been tested by ELISA, Western blot analysis, ICC/IF and Flow cytometry to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. In Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for CBR1

Target: CBR1 (Carbonyl Reductase 1 (CBR1))

Alternative Name: carbonyl reductase 1

Background: Carbonyl reductase 1 (CBR1) is a DPH-dependent, monomeric, and cytosolic enzyme belonging to a family of short-chain dehydrogeses/reductases. This protein consists of 277 amino acid residues and is widely distributed in human tissues such as liver, epidermis, stomach, small intestine, kidney, neurol cells, and smooth muscle fiber. CBR1 metabolizes many toxic environmental quinones and pharmacological relevant substrates such as the anticancer drug, doxorubicin. The best substrates of CBR1 are quinones, including ubiquinone-1 and tocophrolquinone (vitamin E).

UniProt: P16152