CBR1 antibody (Middle Region)

Catalog No. ABIN2782364

Cited in 2+ publications. The Rabbit Polyclonal anti-CBR1 antibody (ABIN2782364) specifically detects CBR1 in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Cow, Pig, Rabbit, Dog, Guinea Pig, Horse and Zebrafish (Danio rerio) samples.

Quick Overview for CBR1 antibody (Middle Region) (ABIN2782364)

Target: CBR1 (Carbonyl Reductase 1 (CBR1))

Reactivity: Human, Mouse, Rat, Cow, Pig, Rabbit, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CBR1 Antibody

Binding Specificity: Middle Region

Purpose: CBR1 Antibody - middle region

Sequence: AEVTMKTNFF GTRDVCTELL PLIKPQGRVV NVSSIMSVRA LKSCSPELQQ

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 79%, Rat: 93%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against CBR1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CBR1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP45800-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-CBR1 antibody (ABIN2782364)

Mitani, Ito, Harada, Nakano, Inui, Ashida, Yamaji: "Resveratrol reduces the hypoxia-induced resistance to doxorubicin in breast cancer cells." in: Journal of nutritional science and vitaminology, Vol. 60, Issue 2, pp. 122-8, (2014) (PubMed).

Lim, Shin, Jo, Jyothi, Nguyen, Choi, Kim, Park, Eun, Yoon, Ha, Kim: "Carbonyl reductase 1 is an essential regulator of skeletal muscle differentiation and regeneration." in: The international journal of biochemistry & cell biology, Vol. 45, Issue 8, pp. 1784-93, (2013) (PubMed).

Target Details for CBR1

Target: CBR1 (Carbonyl Reductase 1 (CBR1))

Alternative Name: CBR1

Background:

Background Information: Carbonyl reductase is one of several monomeric, NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds. This enzyme is widely distributed in human tissues.

Gene Name: Carbonyl reductase 1

Alternative Symbols: CBR, hCBR1, PG-9-KR, SDR21C1

Protein Name: Carbonyl reductase [NADPH] 1

Molecular Weight: 30kDa

Gene ID: 873

NCBI Accession: NP_001748

UniProt: P16152