CNR1 antibody (AA 150-200)

Catalog No. ABIN5540252

This Rabbit Polyclonal antibody specifically detects CNR1 in WB and IHC (p). It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for CNR1 antibody (AA 150-200) (ABIN5540252)

Target: CNR1 (Cannabinoid Receptor 1 (CNR1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CNR1 Antibody

Binding Specificity: AA 150-200

Specificity: This antibody detects endogenous levels of Cannabinoid receptor 1 (region surrounding Phe189).

Purification: Affinity Chromatography

Immunogen: Synthetic peptide corresponding to amino acids 150-200 of Human CB1.

Application Details

Application Notes: Western blot : 1/500-1/1000. Immunohistochemistry on Paraffin sections : 1/50-1/200.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 95 % by SDS-PAGE) Aff - Purified

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for CNR1

Target: CNR1 (Cannabinoid Receptor 1 (CNR1))

Alternative Name: cannabinoid receptor 1

Background: The cannabinoid receptors (CB1 and CB2) are G protein-coupled receptors that inhibit adenylate cyclase activity in response to psychoactive cannabinoids. CB1 is expressed in brain tissue and, in low levels, in testis. CB2 is expressed only by cells of the immune system. The cannabinoid receptors mediate most of the cannabinoid-induced responses in a dose-dependent, stereoselective manner. This response system is thought to be involved in specific brain functions, such as nociception, control of movement, memory and neuroendocrine regulation, as well as having a possible role in brain development. In addition, CB1 may mediate the addictive behavior involved with the use of psychoactive cannabinoids, such as THC in marijuana.

UniProt: P21554

Pathways: Feeding Behaviour