G Protein-Coupled Receptor 1 antibody

Catalog No. ABIN5540349

The Mouse Monoclonal anti-G Protein-Coupled Receptor 1 antibody is suitable to detect G Protein-Coupled Receptor 1 in samples from Human. It has been validated for IHC (p).

Quick Overview for G Protein-Coupled Receptor 1 antibody (ABIN5540349)

Target: G Protein-Coupled Receptor 1 (GPR1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This G Protein-Coupled Receptor 1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: K1G4

Product Details anti-G Protein-Coupled Receptor 1 Antibody

Specificity: This antibody detects GPR1.

Purification: Protein G

Immunogen: DNA vaccine

Isotype: IgG2a

Application Details

Application Notes: Immunohistochemistry on paraffin sections: 10-20 μg/mL (1/25-1/50). Positive control: Human brain cortex.

Restrictions: For Research Use only

Handling

Buffer: Phosphate buffered saline pH 7.2 (PBS) Preservatives: 0.1 % Kathon Stabilizers: 5 mg/mL bovine serum albumin (BSA)

Storage: 4 °C,-20 °C

Storage Comment: Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for G Protein-Coupled Receptor 1

Target: G Protein-Coupled Receptor 1 (GPR1)

Alternative Name: gpr1

Background: GPR1 is a 355 amino acid member of the G - protein coupled receptor 1 family with a seven - transmembrane basic structure. GPR1 is a receptor for the inflammation - associated leukocyte chemoattractant chemerin / RARRES2, suggesting a role for this receptor in the regulation of inflammation. Chemerin is also an adipokine involved in glucose and lipid metabolism. The literature sugests that GPR1 can also act as a coreceptor for HIV - 1.

UniProt: P46091

Pathways: Steroid Hormone Mediated Signaling Pathway, Regulation of Carbohydrate Metabolic Process