GARS antibody (AA 43-289)

Catalog No. ABIN5540351

This Mouse Monoclonal antibody specifically detects GARS in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for GARS antibody (AA 43-289) (ABIN5540351)

Target: GARS (Glycyl-tRNA Synthetase (GARS))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GARS antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: AT4E10

Product Details anti-GARS Antibody

Binding Specificity: AA 43-289

Purification: Protein-A affinity chromatography

Immunogen: Recombinant human GARS (43-289aa) purified from E. coli.

Isotype: IgG1

Application Details

Application Notes: The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for GARS

Target: GARS (Glycyl-tRNA Synthetase (GARS))

Alternative Name: glycyl-trna synthetase

Background: GARS, also known as glycyl-tRNA synthetase, is one of the aminoacyl-tRNA synthetase that charge tRNAs with their cognate amino acids. Defects in the gene encoding GlyRS is the cause of Charcot-Marie-Tooth disease type 2D (CMT2D), which is an autosomal dominant inherited disease characterized by severe weakness, atrophy and absence of deep tendon reflexes in the upper extremities. Defects in the GlyRS gene is also the cause of distal hereditary muscular neuropathy type V (HMN5), a disease similar to CMT2D, though the distal sensory involvement is less severe in HMN5 patients.

UniProt: P41250

Pathways: Ribonucleoside Biosynthetic Process