KCNIP1 antibody (AA 12-22)

Catalog No. ABIN5540452

This anti-KCNIP1 antibody is a Rabbit Polyclonal antibody detecting KCNIP1 in WB and EIA. Suitable for Mouse.

Quick Overview for KCNIP1 antibody (AA 12-22) (ABIN5540452)

Target: KCNIP1 (Kv Channel Interacting Protein 1 (KCNIP1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNIP1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-KCNIP1 Antibody

Binding Specificity: AA 12-22

Sequence: QTKQRRPSKD K

Specificity: This antibody is reactive to the 27 kDa Kchip1 in Mouse and other species with consensus Kchip1 sequence.

Purification: Protein G affinity

Immunogen: A synthetic peptide derived from the amino sequence amino acid 12-22 of mouse Kchip1, conjugated with KLH

Application Details

Application Notes: ELISA: Dilute the antibody approx. 1:300,000 for detection of Kchip1 peptide (QTKQRRPSKDK) coated on ELISA plate. Western blot: Dilute approx. 1:4,000 to detect the 27 kDa Kchip1 in mouse brain extract.

Restrictions: For Research Use only

Handling

Buffer: 0.01M PBS, pH 7.4

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for KCNIP1

Target: KCNIP1 (Kv Channel Interacting Protein 1 (KCNIP1))

Alternative Name: kcnip1,vabp

Background: KChIP1 is an important member of the potassium channel interacting protein family. It binds to and influences the voltage gated potassium (Kv) channel. Like all other members in the family, KChIP1 has calcium binding domains (EF-hand-like) that sense calcium concentrations to regulate Kv channel. KChIP1 frequently forms complex with the rapid inactivating A-type Kv channels. It may play a role in modulating somatodendritic excitability, and the repolarization of cardiac myocytes following action potential. It is also reported that KChIP1 is associated with the GABAergic synapses in hippocampus.