PTPRT antibody (AA 1-742)

Catalog No. ABIN5540588

This Mouse Monoclonal antibody specifically detects PTPRT in WB, FACS, ICC, IF and IP. It exhibits reactivity toward Human, Rat and Pig.

Quick Overview for PTPRT antibody (AA 1-742) (ABIN5540588)

Target: PTPRT (Receptor Protein Tyrosine Phosphatase (PTPRT))

Reactivity: Human, Rat, Pig

Host: Mouse

Clonality: Monoclonal

Conjugate: This PTPRT antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: 3D7

Product Details anti-PTPRT Antibody

Binding Specificity: AA 1-742

Specificity: Monoclonal antibodies 3G4 and 3D7 have been directed against the extracellular domain of RPTPμ.

Purification: Purified

Immunogen: This antibody has been derived by fusion of SP2/0 mouse myeloma cells with spleen cells from a BALB/c mouse immunized with ExG protein, secreted by NIH-3T3 transfected cells and purified with glutahione beads. The cells have been transfected using a fusion construct, termed ExG, encoding the entire ectodomain of the Human RPTPmu molecule (aa 1-742), fused COOH terminally to GST.

Isotype: IgG2a

Application Details

Application Notes: Western blot. Immunoprecipitation. Immunofluorescence. Flow Cytometry.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Buffer System: PBS Preservatives: 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for PTPRT

Target: PTPRT (Receptor Protein Tyrosine Phosphatase (PTPRT))

Alternative Name: ptprt

Background: Receptor-like protein tyrosine phosphatases (RPTPs) represent a new family of transmembrane proteins that are thought to transduce external signals by dephosphorylating phosphotyrosine residues on intracellular substrates. RPTPμ is a prototypic receptor-like protein-tyrosine phosphatase (RPTP) that mediates homotypic cell-cell interactions. Intracellularly, RPTPμ consists of a relatively large juxtamembrane region (about 150 amino acids) and two conserved phosphatase domains. As in most RPTPs, the first (membrane-proximal) PTP domain of RPTPμ is catalytically active, whereas its second (C-terminal) domain is inactive. RPTPμ is involved in cell-cell adhesion through homophilic interactions and may also play a key role in signal transduction and growth control.

UniProt: O14522