PTPRT antibody (C-Term)

Catalog No. ABIN2789503

Product Details anti-PTPRT Antibody

Target: PTPRT (Receptor Protein Tyrosine Phosphatase (PTPRT))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Horse, Rabbit, Zebrafish (Danio rerio), Dog, Guinea Pig, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPRT antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: WPAYRDTPPS KRSLLKVVRR LEKWQEQYDG REGRTVVHCL NGGGRSGTFC

Predicted Reactivity: Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against PTPRT. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1441 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PTPRT

Target: PTPRT (Receptor Protein Tyrosine Phosphatase (PTPRT))

Alternative Name: PTPRT (PTPRT Products)

Synonyms: RPTPrho antibody, RPTP-rfo antibody, mKIAA0283 antibody, protein tyrosine phosphatase, receptor type T antibody, protein tyrosine phosphatase, receptor type, T antibody, PTPRT antibody, Ptprt antibody

Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. The protein domain structure and the expression pattern of the mouse counterpart of this PTP suggest its roles in both signal transduction and cellular adhesion in the central nervous system. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.
Alias Symbols: KIAA0283, RPTPrho
Protein Interaction Partner: CUL3, PTPRN,
Protein Size: 1441

Molecular Weight: 160 kDa

Gene ID: 11122

NCBI Accession: NM_007050, NP_008981

UniProt: O14522