PTMA
Reactivity: Human
ELISA
Host: Rabbit
Polyclonal
Biotin
Application Notes
ELISA: This antibody is reactive to recombinant PTMA protein. Western blot: This antibody is reactive to 38.4KDa GST tagged recombinant PTMA protein.
Restrictions
For Research Use only
Format
Lyophilized
Buffer
0.01M PBS, pH 7.0 without preservatives
Preservative
Without preservative
Storage
4 °C,-20 °C
Storage Comment
Prior to reconstitution store at 2-8°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Expiry Date
12 months
Target
PTMA
(Prothymosin, alpha (PTMA))
Alternative Name
prothymosin alpha
Background
PTMA (prothymosin alpha) is the precursor of thymosin α1. It is an acidic, non-histone nuclear protein with 109-111 amino acids. PTMA is implicated with cell cycle regulation, chromatin remodeling, expression of oxidative stress-response genes and immunomodulation. PTMA is elevated in malignances such as breast cancer, gastric cancer, prostate and bladder cancers. PTMA is a potential biomarker for the prognosis of cancer treatment.