PTMA antibody
Quick Overview for PTMA antibody (ABIN7075306)
Target
See all PTMA AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Cross-Reactivity
- Human, Rat
-
Purification
- Affinity purification
-
Immunogen
- KLH conjugated Synthetic peptide corresponding to Mouse PTMA
-
-
-
-
Application Notes
- IHC/IF (H,M,R) 1:750-1:1500/1:500-1:2000
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- PBS, pH 7.4, 0.02 % sodium azide
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- -20 °C
-
-
- PTMA (Prothymosin, alpha (PTMA))
-
Alternative Name
- PTMA
-
Background
- Prothymosin alpha (PTMA) is a nuclear protein possessing a number of cellular functions including cell survival. PTMA is identified to be localized in the nuclei of neurons, while it is found in both nuclei and cytoplasm in the astrocytes and microglia of adult brai. PTMA inhibits the neuronal necrosis induced by serum-free starvation or ischemia-reperfusion stress, which causes a rapid internalization of GLUT1/4, leading a decrease in glucose uptake and cellular ATP levels.
-
Gene ID
- 19231
-
NCBI Accession
- NP_032998
-
UniProt
- P26350
Target
-