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RanBP3 antibody (AA 235-445)

This anti-RanBP3 antibody is a Mouse Monoclonal antibody detecting RanBP3 in WB and EIA. Suitable for Human.
Catalog No. ABIN5540644

Quick Overview for RanBP3 antibody (AA 235-445) (ABIN5540644)

Target

See all RanBP3 (RANBP3) Antibodies
RanBP3 (RANBP3) (RAN Binding Protein 3 (RANBP3))

Reactivity

  • 24
  • 20
  • 17
  • 1
  • 1
  • 1
  • 1
Human

Host

  • 37
  • 2
Mouse

Clonality

  • 36
  • 3
Monoclonal

Conjugate

  • 20
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This RanBP3 antibody is un-conjugated

Application

  • 37
  • 16
  • 15
  • 13
  • 6
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone

AT12E11
  • Binding Specificity

    • 15
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 235-445

    Specificity

    Recognizes Human RANBP3. Other species not tested.

    Purification

    Protein-A affinity chromatography

    Immunogen

    Recombinant human RANBP3 (235-445aa) purified from E. coli.

    Isotype

    IgG1
  • Application Notes

    The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:500.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

    Expiry Date

    12 months
  • Target

    RanBP3 (RANBP3) (RAN Binding Protein 3 (RANBP3))

    Alternative Name

    ranbp3

    Background

    The GTPase Ran is a small protein that belongs to the RAS protein superfamily and is found associated with the nuclear membrane. Ran GTPase is essential for mRNA processing, nuclear transport, cell cycle control, mitotic spindle assembly, and postmitotic nuclear re-assembly and nuclear architecture maintenance. Ran binding proteins (RanBPs) belong to a family of proteins that bind Ran GTPase and help to stimulate its GTPase activity. Members of the RanBP family show weak similarity to importin beta, a protein involved in the transport of proteins to the nuclear membrane. Recently it has been shown that RanBP3 function is regulated by the Ras/ERK/RSK and PI3K/Akt signaling pathway. This finding has provided a link between nuclear transport, cell signaling, and cell fate.

    UniProt

    Q9H6Z4
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