NPBWR1 antibody

Catalog No. ABIN5540974

The Mouse Monoclonal anti-NPBWR1 antibody (Clone 1F9) (ABIN5540974) specifically detects NPBWR1 in IHC (p). The antibody is reactive with Human samples.

Quick Overview for NPBWR1 antibody (ABIN5540974)

Target: NPBWR1 (Neuropeptides B/W Receptor 1 (NPBWR1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NPBWR1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 1F9

Product Details anti-NPBWR1 Antibody

Specificity: This antibody detects human NPBWR1.

Purification: Affinity Chromatography on Protein G

Immunogen: DNA vaccine

Isotype: IgG2a

Application Details

Application Notes: Immunohistochemistry on paraffin sections: 5 μg/mL (1/80). Predigestion with proteinase K required. Positive control: Human hippocampus.

Restrictions: For Research Use only

Handling

Buffer: Phosphate buffered saline pH 7.2 (PBS) Preservatives: 0.1 % Kathon Stabilizers: 5 mg/mL BSA

Storage: 4 °C,-20 °C

Storage Comment: Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for NPBWR1

Target: NPBWR1 (Neuropeptides B/W Receptor 1 (NPBWR1))

Alternative Name: gpr7

Background: Neuropeptides B/W receptor type 1 (NPBWR1) is a 328 amino acid protein with three potential glycosylation sites and one disulfide bond. It interacts specifically with a number of opioid ligands. Most notably, it is a receptor for neuropeptides B and W, which are involved in neuroendocrine system regulation, food intake and behaviour. The highest expression of GPR7 has been described in the amygdala and hypothalamic nuclei known to regul ate feeding and social behaviour. GPR7 has a higher affinity for neuropeptide B than for neuropeptide W.

UniProt: P48145