FPR3 antibody

Catalog No. ABIN5540982

The Mouse Monoclonal anti-FPR3 antibody has been validated for FACS. It is suitable to detect FPR3 in samples from Human.

Quick Overview for FPR3 antibody (ABIN5540982)

Target: FPR3 (Formyl Peptide Receptor 3 (FPR3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FPR3 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: 2G3

Product Details anti-FPR3 Antibody

Specificity: This antibody detects human FPRL2.

Purification: Protein G purified

Immunogen: DNA vaccine

Isotype: IgG2a

Application Details

Application Notes: FACS. IHC (weak reaction).

Restrictions: For Research Use only

Handling

Buffer: Phosphate buffered saline pH 7.2 (PBS) Preservatives: 0.1 % Kathon Stabilizers: 5 mg/mL bovine serum albumin (BSA)

Storage: 4 °C,-20 °C

Storage Comment: Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for FPR3

Target: FPR3 (Formyl Peptide Receptor 3 (FPR3))

Alternative Name: fprl2

Background: FPRL2 is a 353 amino acid G - protein coupled receptor. Its particular distribution on macrophage subsets of the lung, intestine and skin suggest an involvement in innate immunity against helminths or in allergic diseases. Fittingly, the recept or has also been identified on eosinophils, but not on neutrophils. The endogenous peptide F2L, an acetylated 21 amino acid peptide derived from heme - binding protein, is a most specific ligand for FPRL2 and causes chemotaxis but not degranulation in human eosinophils. F2L is also chemotactic for plasmacytoid dendritic cells which express FPRL2 and up - regulate this receptor during maturation.

UniProt: Q6L5J4