MHC Class I (Monomorphic) antibody (PE)

Catalog No. ABIN5541362

Product Details

Target: MHC Class I (Monomorphic)

Reactivity: Horse

Host: Mouse

Clonality: Monoclonal

Conjugate: PE

Application: Flow Cytometry (FACS)

Specificity: All tissues Species: Equine (Horse).

Purification: Affinity chromatography on Protein A

Immunogen: Equine leucocytes

Clone: CVS22

Isotype: IgG2a

Application Details

Application Notes: Flow cytometry: Neat, use 10 μL to label 10e6 cells in 100 μL.

Restrictions: For Research Use only

Handling

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Prior to and following reconstitution store the antibody at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details

Target: MHC Class I (Monomorphic)

Background: MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44 kDa) with beta 2 microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. Fibroblasts or neurons however only show a low level of antigen.