GFAP antibody

Catalog No. ABIN5541413

This Rabbit Polyclonal antibody specifically detects GFAP in IF, ICC, IHC (p) and IHC (fro). It exhibits reactivity toward Human, Rat, Mouse, Cow, Pig and Guinea Pig.

Quick Overview for GFAP antibody (ABIN5541413)

Target: GFAP (Glial Fibrillary Acidic Protein (GFAP))

Reactivity: Human, Rat, Mouse, Cow, Pig, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GFAP antibody is un-conjugated

Application: Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-GFAP Antibody

Specificity: This antibody stains astrocytes, glial cells, ependymal cells and their corresponding tumors. In the peripheral nervous system , it stains Schwann cells, satellite and enteric glial cells. This antibody distinguishes neoplasm of astrocytes origin from other neoplasm of CNS. Cellular Localization: Cytoplasmic.

Purification: Protein A Chromatography

Immunogen: Purified Human GFAP.

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry. Immunocytochemistry. Suitable for Frozen or Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections and cell smears: 1/50-1/200 using streptavidin~biotin system or polymer system. Recommended Positive Control : Human brain or astrocytoma.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4 Preservatives: 0.05 % Sodium Azide Stabilizers: 1 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: One year from despatch.

Target Details for GFAP

Target: GFAP (Glial Fibrillary Acidic Protein (GFAP))

Alternative Name: gfap

Background: Gilial Fibrillary acidic protein (GFAP), a 51 kDa an intermediate filament protein is closely related to non-epithelial family members, Vimentin, desmin and peripherin, which are all involved in structure and function of cell cytoskeleton. GFAP is expressed in central nervous system (CNS) in the astrocytes cells, functioning in cellular processes e.g. cell structure, movements, cell communication, brain processes and brain functions.

UniProt: P14136