DGKA antibody (C-Term, Catalytic Domain)

Catalog No. ABIN5541797

This Mouse Monoclonal antibody specifically detects DGKA in WB and IP. It exhibits reactivity toward Human.

Quick Overview for DGKA antibody (C-Term, Catalytic Domain) (ABIN5541797)

Target: DGKA (Diacylglycerol Kinase, alpha 80kDa (DGKA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DGKA antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: M5a

Product Details anti-DGKA Antibody

Binding Specificity: C-Term, Catalytic Domain

Specificity: This Monoclonal M5a Antibody is directed against the C-terminal portion (part of the catalytic domain) of Rat DGK alpha.

Purification: Purified

Immunogen: Escherichia coli cell-expressed, affinity-purified Glutathione S-transferase fusion protein of a C-terminal portion (part of the catalytic domain) of Rat DGKu.

Isotype: IgG2a

Application Details

Application Notes: Western blot. Immunoprecipitation.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Buffer System: PBS Preservatives: 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for DGKA

Target: DGKA (Diacylglycerol Kinase, alpha 80kDa (DGKA))

Alternative Name: dag kinase alpha

Background: Diacylglycerol kinase alpha is an enzyme that in humans is encoded by the DGKA gene. The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It acts as a modulator that competes with protein kinase C for the second messenger diacylglycerol in intracellular signaling pathways. It also plays an important role in the resynthesis of phosphatidylinositols and phosphorylating diacylglycerol to phosphatidic acid. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. Tissue specificity: lymphocytes and oligodendroglial cells. Diacylglycerol kinases are involved in cell signaling, either as regulators of diacylglycerol levels or as intracellular signal-generating enzymes.

UniProt: P23743