GPR50 antibody

Catalog No. ABIN5541840

The Mouse Monoclonal anti-GPR50 antibody has been validated for IHC (p). It is suitable to detect GPR50 in samples from Human.

Quick Overview for GPR50 antibody (ABIN5541840)

Target: GPR50 (G Protein-Coupled Receptor 50 (GPR50))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GPR50 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 1A3

Product Details anti-GPR50 Antibody

Specificity: This antibody detects Human GPR50.

Purification: Protein G

Immunogen: DNA vaccine

Isotype: IgG1

Application Details

Application Notes: Immunohistochemistry on paraffin sections: 5 μg/mL. Positive control: Human placenta.

Restrictions: For Research Use only

Handling

Buffer: Phosphate buffered saline pH 7.2 (PBS) Preservatives: 0.1 % Kathon Stabilizers: 5 mg/mL bovine serum albumin (BSA)

Storage: 4 °C,-20 °C

Storage Comment: Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for GPR50

Target: GPR50 (G Protein-Coupled Receptor 50 (GPR50))

Alternative Name: gpr50

Background: GPR50 or me latonin - related receptor is a 617 amino acid protein that belongs to the G - protein coupled receptor 1 family, containing one disulfide bond. GPR50 does not bind melatonin and its end ogenous ligand is still unknown. Nevertheless, this receptor has been shown to behave as an antagonist of the melatonin receptor MT 1. GPR50 has been identified as a genetic risk factor for bipolar disorder and major depression in women, and it has been linked to neurite outgrowth, lipid metabolism, stress response and energy homeostasis and torpor. Its expression seems to be limited to brain, particularly the hypothalamus and pituitary.

UniProt: Q13585