PGAM1 antibody (AA 1-254)

Catalog No. ABIN5542084

This anti-PGAM1 antibody is a Mouse Monoclonal antibody detecting PGAM1 in WB, ICC, IF, FACS and EIA. Suitable for Human.

Quick Overview for PGAM1 antibody (AA 1-254) (ABIN5542084)

Target: PGAM1 (phosphoglycerate Mutase 1 (Brain) (PGAM1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PGAM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Clone: AT1G4

Product Details anti-PGAM1 Antibody

Binding Specificity: AA 1-254

Purification: Protein-A affinity chromatography

Immunogen: Recombinant human PGAM1 (1-254aa) purified from E. coli.

Isotype: IgG2a

Application Details

Application Notes: The antibody has been tested by ELISA, Western blot analysis, ICC/IF and Flow cytometry to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. In Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for PGAM1

Target: PGAM1 (phosphoglycerate Mutase 1 (Brain) (PGAM1))

Alternative Name: pgam1

Background: PGAM1 belongs to the phosphoglycerate mutase family. This protein is important components of glucose and 2,3-BPGA (2,3-bisphosphoglycerate) metabolism and catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). Mutations in this protein cause muscle phosphoglycerate mutase eficiency, also known as glycogen storage disease X.

UniProt: P18669

Pathways: Regulation of Carbohydrate Metabolic Process