PSG1 antibody

Catalog No. ABIN5542089

The Mouse Monoclonal anti-PSG1 antibody is suitable to detect PSG1 in samples from Human. It has been validated for IF, ICC, FACS and IHC (fro).

Quick Overview for PSG1 antibody (ABIN5542089)

Target: PSG1 (Pregnancy Specific beta-1-Glycoprotein 1 (PSG1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PSG1 antibody is un-conjugated

Application: Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: BAP3

Product Details anti-PSG1 Antibody

Specificity: This antibody reacts to Pregnancy-specifc Glycoproteins (PSG1-11). Species: Human.

Purification: Affinity chromatography on Protein G

Immunogen: Immunisation with extracted protein of human PSG

Isotype: IgG1

Application Details

Application Notes: Flow cytometry: 1.2 μg/10e6 cells.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate buffered saline, pH 7.2

Storage: 4 °C,-20 °C

Storage Comment: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for PSG1

Target: PSG1 (Pregnancy Specific beta-1-Glycoprotein 1 (PSG1))

Alternative Name: cd66f,psg1

Background: The human pregnancy-specific glycoprotein family (PSG) is a group of closely related secreted glycoproteins which are highly expressed in placental syncytiotrophoblast cells of fetal origin (1). PSG are commonly expressed in tumors of trophoblast origin (hydatidiform mole, choriocarci-noma). They represent the most abundant fetal protein in the maternal blood at term. Together with the carcinoembryonic antigen (CEA)-related cell adhesion molecule (CEACAM) genes, the human PSG genes form the CEACAM gene family (2). PSG stimulate secretion of TH2-type cytokines from monocytes. CD9 was shown to represent the monocyte receptor for murine PSG17 (3). PSG are thought to modulate the maternal immune system during pregnancy thus protecting the semiallotypic fetus from rejection (4).

UniProt: P11464