Transglutaminase 2 antibody (Biotin)

Catalog No. ABIN5542234

The Biotin-conjugated Rabbit Polyclonal anti-Transglutaminase 2 antibody (ABIN5542234) specifically detects Transglutaminase 2 in WB and EIA. The antibody is reactive with Human samples.

Quick Overview for Transglutaminase 2 antibody (Biotin) (ABIN5542234)

Target: Transglutaminase 2 (TGM2) (Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Transglutaminase 2 antibody is conjugated to Biotin

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-Transglutaminase 2 Antibody (Biotin)

Specificity: Reacts with Human 77 kDa TGM2 protein. This antibody does not cross reacts with Guinea Pig or any isoformes.

Purification: Affinity Chromatography on Protein A

Immunogen: A 15 residue synthetic peptide derived from specific domain of Human TG2 protein

Application Details

Application Notes: ELISA. Western Blot.

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: 4 °C,-20 °C

Storage Comment: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for Transglutaminase 2

Target: Transglutaminase 2 (TGM2) (Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))

Alternative Name: transglutaminase-2 (tgm2)

Background: Transglutaminase II catalyzes calcium-dependent post-translational modification of proteins by formation of an isopeptide bond within or between polypeptide chains. It is also known as TGC, tTG, type II-, Gh, cytosolic-, liver-, endothelial-, erythrocyte-, cellular-transglutaminase. Different tissues and cell types express varying amounts of tissue transglutaminase with a markedly hugh expression in rheumatoid lesions. It is implicated in programmed cell death, signal transduction, drug-resistance, cell growth, endocytosis, insulin secretion, cell adhesion, cataract formation, and wound healing.

UniProt: P21980

Pathways: Tube Formation, Thromboxane A2 Receptor Signaling