ANAPC10 antibody (AA 1-185)

Catalog No. ABIN5542270

This anti-ANAPC10 antibody is a Mouse Monoclonal antibody detecting ANAPC10 in WB, ELISA, IHC, ICC and FACS. Suitable for Human.

Quick Overview for ANAPC10 antibody (AA 1-185) (ABIN5542270)

Target: ANAPC10 (Anaphase Promoting Complex Subunit 10 (ANAPC10))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ANAPC10 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: 8F1D10

Product Details anti-ANAPC10 Antibody

Binding Specificity: AA 1-185

Purpose: ANAPC10 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human ANAPC10 (AA: 1-185) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for ANAPC10

Target: ANAPC10 (Anaphase Promoting Complex Subunit 10 (ANAPC10))

Alternative Name: ANAPC10

Background: ANAPC10 is a core subunit of the anaphase-promoting complex (APC), or cyclosome, a ubiquitin protein ligase that is essential for progression through the cell cycle. APC initiates sister chromatid separation by ubiquitinating the anaphase inhibitor securin (PTTG1, MIM 604147) and triggers exit from mitosis by ubiquitinating cyclin B (CCNB1, MIM 123836), the activating subunit of cyclin-dependent kinase-1 (CDK1, MIM 116940) (summary by Wendt et al., 2001 [PubMed 11524682]).

Molecular Weight: 21.3 kDa

UniProt: Q9UM13

Pathways: M Phase